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It is the wholesale substitution of consumer enthusiasm for clinical evidence
Many plans additionally require a trial of a preferred alternative agent and documented follow-up with demonstrated response for continued authorization
13 Although evidence suggests that GLP-1 RAs may have neuroprotective properties and delay disease progression, this was based on a few small phase II studies
Endocrinology 136(8):35853596 Lau J et al (2015) Discovery of the once-weekly glucagon-like peptide-1 (GLP-1) analogue semaglutide
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